ICSI (Intra-Cytoplasmic Sperm Injection)

ICSI is a micromanipulation technique where an individual sperm is injected into an individual egg.. Before ICSI, men with a very low sperm count had a poor chance of fathering a child even with other reproductive technologies. With ICSI, only one motile sperm for each egg retrieved is needed. This enables men with very poor sperm counts to achieve fertilisation, produce embryos suitable for transfer, pregnancy and the birth of healthy children. ICSI can be performed using sperm retrieved by testicular sperm extraction in men with azoospermia (lack of sperm ejaculate).

ICSI can be carried out on eggs retrieved through stimulated or natural cycles and is often recommended in those who have experienced failed fertilisation using standard IVF.